AutoDTCs – OBD-II Trouble Code LookupAutoDTCs – OBD-II Trouble Code Lookup
  • Home
  • DTC Codes
    • Powertrain (P-Codes)
    • Body (B-Codes)
    • Chassis (C-Codes)
    • Network (U-Codes)
  • Diagnostic Guides
  • About
  • Brands
    • Toyota
    • Lexus
    • Hyundai
    • Kia
    • BYD
    • Skoda
    • Mitsubishi
    • Volvo
    • Nissan
    • Mercedes-Benz
    • Dodge
    • Suzuki
    • Honda
    • Volkswagen
    • Audi
    • Chrysler
    • Jeep
    • Ford
  • Contact
  • Home
  • DTC Codes
    • Powertrain (P-Codes)
    • Body (B-Codes)
    • Chassis (C-Codes)
    • Network (U-Codes)
  • Diagnostic Guides
  • About
  • Brands
    • Toyota
    • Lexus
    • Hyundai
    • Kia
    • BYD
    • Skoda
    • Mitsubishi
    • Volvo
    • Nissan
    • Mercedes-Benz
    • Dodge
    • Suzuki
    • Honda
    • Volkswagen
    • Audi
    • Chrysler
    • Jeep
    • Ford
  • Contact
Home / DTC Codes / Powertrain Systems (P-Codes) / GMC Sierra 1500 P0300 — Random Multiple Misfire

GMC Sierra 1500 P0300 — Random Multiple Misfire

GMC logoGMC-specific code — factory diagnostic data
DTC Data Sheet
CodeP0300
VehicleGMC Sierra 1500 (2007-2019)
Engine4.8L / 5.3L / 6.2L V8 (LS-family, Gen-IV, AFM)
SystemIGNITION SYSTEM
Fault typePerformance
Official meaningRandom / Multiple Cylinder Misfire Detected

Last updated: May 14, 2026

Definition source: GMC factory description. Diagnostic guidance is based on factory-defined fault logic for this code.

🔍Decode any GMC Sierra 1500 VIN — free recalls, specs & safety ratings — free VIN decoder with NHTSA data

⚠ Scan tool requirement: This is a GMC-specific code. A generic OBD2 reader will retrieve the code but cannot access the module-level data, live PIDs, or bi-directional tests needed for diagnosis. A professional-grade scan tool with GMC coverage is required for complete diagnosis.

↗Looking for the cross-vehicle definition? Read the generic P0300 article for the SAE-defined fault logic that applies to all manufacturers.

P0300 Quick Answer

The Sierra 1500 shares the AFM-equipped 5.3L (LC9, L83) and 6.2L (L86) V8 engines with the Silverado, so P0300 has the same dominant causes: collapsed AFM lifters on cylinders 1/4/6/7, oil-fouled spark plugs from AFM oil consumption, and individual coil failures. Diagnostic order is the same; the fix list is the same; the cost band is the same.

What Does P0300 Mean on a GMC Sierra 1500?

The GMC Sierra 1500 (2007-2019) stores P0300 when the PCM detects the condition described above. This guide focuses on the 4.8L / 5.3L / 6.2L V8 (LS-family, Gen-IV, AFM) — the most common configuration on this platform. Diagnostic priorities and likely root causes differ from the generic SAE definition because of platform-specific failure patterns documented below.

Symptoms

  • Rough idle (especially cold start)
  • Top-end tick on AFM trucks
  • Hesitation under acceleration
  • Flashing CEL under load = stop driving
  • Possible P030x specific-cylinder codes
  • Fuel economy drop

Common Causes (Most Likely on This Model First)

The Sierra 5.3L V8 misfire failure pattern matches its Silverado twin. Order of likelihood:

  1. Collapsed AFM lifter on cylinder 1, 4, 6, or 7. These are the AFM-deactivation cylinders. The lifter loses oil pressure and stops following the cam profile. Tell: ticking on cold start plus P0300 plus a specific P030x for the affected cylinder.
  2. Stuck VLOM solenoid. Controls oil flow to AFM lifters; a stuck solenoid leaves a lifter in the wrong state.
  3. Oil-fouled spark plugs. AFM oil consumption contaminates the plugs on deactivated cylinders. Replace plugs at 60k-80k on AFM Sierras (not the OE 100k).
  4. Failing ignition coil. COP coils fail one at a time; usually a specific-cylinder P030x appears first.
  5. Vacuum leak at intake gasket. Gen-IV LS intake gaskets shrink at the front and rear corners.
  6. Failing fuel pump (older trucks). Check fuel pressure under load.

Diagnostic Approach

  1. Read freeze frame — note RPM and load at fault. Idle-only = AFM / ignition; load-only = fuel pressure / injector.
  2. Pull misfire counters per cylinder. Pattern on 1/4/6/7 = AFM. Single-cylinder dominance = coil/plug/injector for that cylinder.
  3. LTFT both banks > +10% = vacuum leak.
  4. Listen for top-end tick on AFM-equipped engines. Collapsed lifter is unmistakable.
  5. Pull plugs on misfiring cylinders — oily wet residue confirms AFM oil consumption.
  6. Swap a suspected coil to a known-good cylinder. If misfire follows, replace it.
  7. Smoke-test intake if both banks lean.

Possible Fixes

FixWhen
AFM lifter replacement / AFM-deleteTick on cold start + misfire on 1/4/6/7
Spark plugs (set of 8)Plugs > 60k miles on AFM Sierra
Single ignition coilMisfire follows when swapped
Intake manifold gasketBoth-bank LTFT > +10%
VLOM solenoidAFM-related misfire with no lifter tick

Can I Still Drive With P0300?

Steady CEL: drive to a shop within a week. Flashing CEL: don’t drive — severe misfire damages the catalyst quickly. Extended driving with a collapsed AFM lifter can score the camshaft and turn a $1,400 job into a $4,000+ job.

How Serious Is This Code?

Moderate to high. Always investigate whether AFM lifter failure is the cause — if it is, the longer it runs, the more expensive the fix becomes.

Repair Costs

RepairEstimated cost (parts + labor)
Spark plug replacement (8 OE)$180 – $340
Single ignition coil$95 – $180
All 8 coils + plugs$520 – $880
AFM lifter service (one bank)$1,400 – $2,400
AFM-delete kit$1,800 – $3,500
Intake manifold gaskets$420 – $780

Related Random Multiple Codes

Compare nearby Gmc random multiple trouble codes with similar definitions, fault patterns, and diagnostic paths.

  • P0300 – Honda CR-V P0300 — Random Multiple Misfire
  • P1399 – Honda Civic P1399 — Honda Random Misfire
  • P0306 – Ram 1500 P0306 — Cylinder 6 Misfire
  • P0303 – Ram 1500 P0303 — Cylinder 3 Misfire

FAQ

Why does my GMC Sierra have P0300?

On the AFM-equipped 5.3L (and 6.2L) Sierra, the leading cause is a collapsed AFM lifter on cylinders 1, 4, 6, or 7. Oil-fouled spark plugs from the same AFM oil-consumption pattern are second. Individual ignition coil failures and vacuum leaks are third and fourth.

Should I delete AFM on my Sierra 1500?

AFM-delete is the standard fix for the recurring lifter problem on 2007-2019 Sierras with AFM-equipped engines. It costs $1,800-$3,500 done correctly (cam swap, non-AFM lifters, PCM tune) and removes the failure mode permanently. Worth doing on out-of-warranty trucks past 80k miles.

Can a Sierra run with a flashing CEL?

It can, but it shouldn’t. A flashing Check Engine Light during a misfire means raw fuel is reaching the catalytic converter and overheating the substrate. The cat can fail in 15-30 minutes of continued driving. Pull over and arrange a tow.

How often should I change spark plugs on a 5.3L Sierra with AFM?

GM specs 100,000 miles, but on AFM-equipped engines the plugs foul faster from oil consumption. Replace at 60,000-80,000 miles to avoid misfire codes. All 8 at once; never half.

Diagnostic Guides for This Code

In-depth step-by-step tutorials that pair with P0300.

  • Diagnose Misfires with Scan-Tool DataRead guide →
  • Test an Ignition Coil ProperlyRead guide →
  • Test a Fuel Injector ElectricallyRead guide →

Decode any GMC Sierra 1500 VIN

Free recalls, specs & safety ratings — no signup.

Decode VIN →

Featured Guides
  • Fuel Trim: Short vs. Long Term
  • Diagnose Misfires (Scan Tool)
  • Diagnose EVAP Faults
  • CAN Bus: The 60-Ohm Rule
  • Test a Wheel Speed Sensor
  • Read Freeze Frame Data
Popular Codes
  • P0420 — Catalyst Efficiency
  • P0300 — Random Misfire
  • P0171 — System Lean (Bank 1)
  • P0455 — EVAP Large Leak
  • P0128 — Coolant Below Thermostat
  • U0121 — Lost Comm with ABS
  • C0040 — Wheel Speed Sensor (RR)
  • P0016 — Crank/Cam Correlation
All Categories
  • Steering Systems
  • Suzuki
  • Powertrain Systems (P-Codes
  • Suspension Systems
  • Ford
  • Body Systems (B-Codes
  • Wheels / Driveline
  • Volvo
  • Chassis Systems (C-Codes
  • CAN Bus / Network Communication
  • Audi
  • Network & Integration (U-Codes
  • Control Module Communication
  • Skoda
  • Engine & Powertrain
  • Vehicle Integration Systems
  • Jeep
  • Fuel & Air Metering
  • Volkswagen
  • Honda
  • Ignition & Misfire
  • Mitsubishi
  • Chrysler
  • Emission System
  • BYD
  • Chevrolet
  • Transmission
  • Toyota
  • GMC
  • Hybrid / EV Propulsion
  • Lexus
  • Ram
  • Cooling Systems
  • Mercedes-Benz
  • Body / Comfort & Interior
  • Dodge
  • Airbag / SRS
  • Kia
  • Climate Control / HVAC
  • Hyundai
  • ABS / Traction / Stability
  • Nissan
Powertrain Systems
  • Engine & Powertrain
  • Fuel & Air Metering
  • Ignition & Misfire
  • Emission System
More Systems
  • Transmission
  • Hybrid / EV Propulsion
  • Cooling Systems
  • Body / Comfort & Interior
Safety & Chassis
  • Airbag / SRS
  • Climate Control / HVAC
  • ABS / Traction / Stability
  • Steering Systems
Chassis & Network
  • Suspension Systems
  • Wheels / Driveline
  • CAN Bus / Network Communication
  • Control Module Communication
  • © 2026 AutoDTCs.com. Accurate OBD-II DTC Explanations for All Makes & Models. About · Contact · Privacy Policy · Disclaimer